Located in North Yorkshire, England, to the west of York, Acomb is a village and suburb that is part of the City of York unitary authority area. The Domesday Book of 1086 mentions the location of the old settlement with the same name. The suburbs of Woodthorpe to the south, Clifton to the north, and Holgate to the east enclose it. The fields along the A1237, York Outer Ring Road, form the western boundary.

Acomb, which had previously been a part of the West Riding of Yorkshire, became a part of the City of York in 1934.

In the 19th and 20th centuries, Acomb, which was once an agricultural community, grew into a dormitory location for workers in heavy industries like rail engineering. More recently, it has accommodated a more varied workforce. It boasts a varied shopping centre even though it no longer has any large-scale manufacturing. Within its limits are at least 19 Grade II listed structures. The village charm of the historic district along Front Street and the Green was preserved when it was designated as a conservation area in 1975. The Ancient Monuments and Archaeological Areas Act of 1979 additionally designates it as an Area of Archaeological Importance.

Acomb is made up of the City of York's Acomb and Westfield wards. With 22,215 residents, it was the most populated region in the city according to the 2011 England and Wales census. One comprehensive school and six elementary schools are present. In addition, there is one public sports facility and several sports clubs.